… associated with immunity, disease risk and mortality. In conclusion, our analysis in the UK
Biobank identifies intriguing predictors of … of postzygotic loss of the male Y chromosome. These …

… associated with incidence of solid tumors in the UK Biobank, … and mortality in the UK Biobank
also noted an association … of cells affected by mLOY and increased risk of mortality (17). …

… 223,338 men from the UK Biobank. We scanned Y chromosomes for deviations in genotyping
… A total of 3,789 (1.7%) men showed evidence for mLOY with median chromosome Y LRR …

… associations between mLOY and clinical measures, here the composition of the classical
hematologic compartments in the UK Biobank, … to evaluate the association of mLOY with blood …

… leukocytes often show mosaic loss of chromosome Y (LOY) in … of the men above the age of
70 years, in the UK Biobank [5]. … are associated with increased risk for all-cause mortality [4, 9]…

… the UK population. Thirty-seven of these 39 variants had the same effect direction in UK
Biobank … We therefore analyzed whether the associations between mLRR-Y and mortality were …

… of mLRR-Y scores estimated in 245,349 women from the UK Biobank study (Supplementary …
This did not produce any significant associations after Bonferroni correction across the 156 …

… can be aided by studies that address the mosaic loss of chromosome Y (mLOY) in the
blood… of the UK Biobank study. This research was conducted using the UK Biobank Resource …

… males (19.6%) with mosaic chromosome Y loss (mLOY) and 12,550 females (4.8%) with …
directly to the UK Biobank. Statistically significant associations between mosaicism and health …

… , and mortality. While the public health impact and disease … genetic predisposition has
been strongest for mosaic loss of … in the UK Biobank showed that several CHIP-associated …